Job description
POSITION OVERVIEW
We are seeking a driven and talented candidate to join our Analytical and Formulation Development group in La Jolla, CA. In this role, the Research Associate will focus on the execution of LC-UV and LC-MS for protein assays. As a contributor, s/he will collaborate with other functional groups in support of platform development, strain engineering, upstream, and downstream process development based on defined project goals and within established timelines.
KEY RESPONSIBILITIES
Perform routine protein titer and fidelity assays using LC-UV and LC-MS.
Participate in assay development and carry out protein-based assays (BCA, nanodrop, CE-SDS, ELISA).
Perform daily & weekly operator maintenance on instruments used in support of method development and routine sample analysis and perform troubleshooting with vendor technical support as needed.
Manage and maintain required reagents and laboratory environment to carry out assignments.
Prepare analytical reports and present scientific results in team, project, and inter-site meetings as needed.
Collaborate with internal teams and provide support to different functional groups as needed.
Author and maintain Standard Operating Procedures.
Maintain electronic laboratory notebook adhering to good documentation standards.
EDUCATION / EXPERIENCE
B.S. in a physical or biological science related field plus a minimum of 1 year relevant industry experience
Hands-on experience with LC based assays (RP, SEC, IEX) is required.
Proficiency with the use of chromatography data systems for acquisition method setup, data acquisition, and data processing (e.g. Chromeleon) is required.
Experience in LC-MS analysis of intact proteins is highly desirable.
Ability to follow SOPs and perform testing in a highly accurate and reproducible manner.
Excellent organization skills, detailed oriented, ability to multi-task and manage multiple projects according to established timelines.
Effective problem solving/troubleshooting skills required.
Familiarity with protein/peptide assay development and optimization is a plus.
Experience in CE for the separation of proteins will be beneficial.
Excellent computer skills, proficiency with MS office.
Good oral and written communication skills.
At Sanofi R&D North America, we deliver meaningful solutions for patients. We transform science into breakthrough, best-in-class and first-in-class medicines and vaccines. We believe in creating a diverse and inclusive workforce – and workplace – which brings together the collective brainpower of over 2,000 colleagues and provides you with an exciting place to grow and develop. We set the bar high, and we deliver. Join us and together we will build on our trusted legacy of breakthroughs for society.
Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
As a healthcare company and a vaccine manufacturer, Sanofi has an important responsibility to protect individual and public health. All US based roles require individuals to be fully vaccinated against COVID-19 as part of your job responsibilities.
According to the CDC, an individual is considered to be “fully vaccinated” fourteen (14) days after receiving (a) the second dose of the Moderna or Pfizer vaccine, or (b) the single dose of the J&J vaccine. Fully vaccinated, for new Sanofi employees, is to be fully vaccinated 14 DAYS PRIOR TO START DATE.
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At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.
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