45%- this is the number of deaths attributable to fibrotic disorders worldwide across all organs and are the result of dysregulation of the extracelluar matrix in response to acute and chronic injury. We are building a dedicated research group within Disease Area X focused on delineating the key factors/pathways involved in fibrotic diseases and developing transformative new therapies for patients. The successful candidate will join a team working to discover and progress the next wave of new therapeutics that will halt fibrotic diseases across multiple organs.

We seek candidates who have backgrounds in progressing drug discovery projects from target concept and validation, to discovery and optimization of novel therapeutic modalities, and delivering drug candidates for pre-clinical studies. A track record of hands-on mentorship and development of other scientists is essential to success in the role. Other key skills include a proven ability to formulate and implement project strategy in collaboration with stakeholders, to lead decision-making for project teams, to design and plan experiments in collaboration with bench scientists, and to build effective teams directed towards solving complex scientific problems.

The successful candidate will lead and mentor multiple scientists, work collaboratively across DAx, other NIBR Disease areas and Functional areas, establish external partnerships (academic and biotech), and interact with a global network of researchers working towards the understanding and discovery of novel therapeutics that address fibrosis across multiple organs.

Key responsibilities:

• Formulate novel approaches to targeting fibrosis across multiple organ types
• Lead multi-disciplinary project team to decision milestones
• Line management responsibility for several research scientists

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

What You'll Bring to the Role:

• Ph.D, MD/Ph.D, or equivalent training
• Postdoctoral experience with at least 3 years of experience in industry or equivalent
• Experience in various phases of drug discovery including target identification and validation, designing fit-for-purpose drug discovery flow charts comprising cell and biochemical assays, and the ability to enable deep mechanistic and pharmacological characterization of lead candidates
• Team orientated and collaborative work ethic
• Demonstrated ability to coach and empower others including development of early career scientists
• Demonstrated, successful leadership of project teams

Desirable Skills:

• Expertise in cellular biology, immunology/autoimmunity, fibrosis biology and/or drug discovery
• Experience in single cell approaches to target / pathway identification
• Experience integrating patient data to delineate and validate key drivers of disease
• Demonstrated expertise in diverse molecular and cellular techniques for target and drug discovery (flow cytometry, gene editing, complex cell-based models, etc.)

Why Consider Novartis?

766 million. That’s how many lives our products touched in 2021. And while we’re proud of that fact, in this world of digital and technological transformation, we must also ask ourselves this: how will we continue to improve and extend even more people’s lives?

We believe the answers are found when curious, courageous and collaborative people like you are brought together in an inspiring environment. Where you’re given opportunities to explore. Where you’re empowered to take smart risks, and where you’re surrounded by people who share your determination to tackle the world’s toughest medical challenges.

Imagine what you could do at Novartis!

Commitment to Diversity & Inclusion:

Novartis embraces diversity, equal opportunity and inclusion. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration, and empowers our people to unleash their full potential.

The pay range for this position at commencement of employment is expected to be between $107,200 and $177,600 per year; however, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. The total compensation package for this position may also include other elements, including a sign-on bonus, restricted stock units, and discretionary awards in addition to a full range of medical, financial, and/or other benefits (including 401(k) eligibility and various paid time off benefits, such as vacation, sick time, and parental leave), dependent on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Novartis Institutes for BioMedical Research

DAX - NIBR

USA

Cambridge, MA

NIBRI

Research & Development

Full Time

Regular

No

No