Our laboratory is focused on developing a vaccine for persons at risk of becoming infected with the fungal pathogen Cryptococcus. Cryptococcus has been recently identified by the World Health Organization (WHO) as a priority fungal pathogen. We use mouse models to evaluate different vaccine formulations and maintain a mouse colony of about a dozen different strains in support of our studies. The studies that we do involve working with mice and in evaluating their cellular responses to vaccination and infection. Some studies look at immune responses from white blood cells obtained from research subjects. Various techniques that we use routinely include microscopy, flow cytometry, ELISA, cell-based immunoassays and protein expression and purification of recombinant proteins for vaccines. Here is a link to the lab for more information https://www.umassmed.edu/levitzlab/

Under the direction of the Principal Investigator or Designee, the Research Associate I performs a variety of complex research experiments.

• Perform laboratory experiments and may be responsible for a single research project
• Utilize all software relevant to experiment and equipment used
• Interpret data, form conclusions and decide on next steps under the direction of the PI or designee
• Maintain accurate records, may modify protocols with the approval of the PI or designee
• Review literature, publications and grants relevant to assigned projects
• Record results according to established lab, sponsor & university protocol
• Assist with performing data analysis and/or mathematical computations
• Maintain a detailed lab notebook according to lab practice
• Present findings at lab/group meetings
• Monitor laboratory supply levels and order as noted
• Prepare and label buffers, media, solutions, etc.
• Assist with and comply with all safety regulation and infection control standards
• Train on IACUC, IRB, EHS, Radiation safety protocols
• Comply with all applicable state, federal university, and sponsor policies and agreements
• Provide support with identifying problems and challenges, propose resolutions, implement appropriate solutions
• Provide support with drafting standard operation procedures in compliance to EHS regulation specific for the lab
• Perform other duties as required

• Bachelor’s degree in Biological or Natural Science, or equivalent experience
• Basic understanding of lab safety and protocols
• Knowledge of Microsoft Office products
• Ability to analyze data in a quantitative and objective manner.
• Ability to work in a team environment
• Willingness to work with laboratory mice