Job description

Reporting to the Manufacturing Manager, the RNA Manufacturing Associate (MA) is a motivated self-starter who takes initiative, asks questions, seeks answers, and can make headway at the lab bench. The RNA Manufacturing Associate will work on a team to purify and scale up RNA production in a biotech laboratory environment. In addition, the MA is involved in the development and use of methods to quality control RNA.
Responsibilities

• Initiate, fulfill, and complete client work orders as directed
• Perform analytical methods to quality control RNA products
• Design and review process initiatives and experiments when required
• Create and optimize plasmid and mRNA synthesis workflows
• Plan and track usage of critical reagents/supplies, including plasmids and mRNA
• Operate as a key player in cutting-edge mRNA manufacturing techniques
• Report on project status and product critical quality attributes (CQAs)
• Enjoy the benefits of living in Vermont and being a part of a rapidly growing mRNA CDMO!

Desired skills and background

• Bachelors or Masters in cell or molecular biology, biomedical or chemical engineering, biochemistry, or a related field
• mRNA: synthesis and purification, working knowledge of mRNA biology (e.g. sequence, structure)
• Molecular biology: Polymerase chain reaction (PCR), qPCR, RT-PCR, molecular cloning (e.g. Gibson or Golden Gate), agarose gel electrophoresis, Fragment analyzer
• Protein chemistry: polyacrylamide gel electrophoresis (PAGE), western blotting, other forms of immunoblotting (e.g. dot and slot blots), silver staining, AKTA or FPLC purification, Bioanalyzer
• Cell biology: cell line and primary cell culture maintenance, expansion, banking, transfection optimization
• Automation experience will be a differentiator
• High attention to detail including planning, executing, and documenting experiments
• Communication skills including protocol writing and use of MS Office (Excel, Word, PowerPoint)
• Experience in Master Control and/or SAP a major plus, but not required

At Vernal, you will offer knowledge-based solutions to help us address the growing demand for mRNA, lipid nanoparticle (LNP) mRNA, drug screening, and ultimately clinical supply of mRNA. Together, we will create the most integrated solution for mRNA vaccines and therapeutic R&D. Vernal will become the only one-stop-shop for our clients’ and partners’ mRNA needs, from concept all the way to clinical trials. The mRNA research associate or scientist will develop methods to synthesize, purify, and scale up mRNA. As a startup, we are seeking adaptable, creative thinkers who can independently foresee gaps and opportunities and who take the initiative to solve problems with a sense of urgency. We expect the work to be rewarding, fast-paced, and to offer ample opportunities to plan and create new solutions to help grow our business. Vernal will pay a competitive salary with generous benefits including health, dental, and vision insurance. Although hiring level will depend on experience, we expect to grow with our employees and are interested in a variety of backgrounds.
Vernal Biosciences is located in Colchester, Vermont, adjacent to Burlington which is home of the University of Vermont and the UVM Medical Center. Check out https://www.helloburlingtonvt.com/ for more information. The Burlington area, set on the shores of Lake Champlain, features the best of two worlds:

• Multicultural hub with great schools, restaurants, breweries, shopping, arts, and an affordable cost of living

• Gateway to the Green Mountains including world class hiking, camping, bicycling, and alpine and Nordic skiing

Please contact careers@vernal.bio* with CVs or for more information*

Job Type: Full-time

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